NUGRAHA, RANGGA (2025) DESAIN SISTEM TATA UDARA BERBASIS ANALISIS PSIKROMETRIK DAN SIMULASI HOURLY ANALYSIS PROGRAM (HAP) UNTUK MENCEGAH KONDENSASI DI RUANG BERSIH INDUSTRI FARMASI. S1 thesis, Universitas Mercu Buana Jakarta.
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Abstract
The air handling system is a crucial component in the pharmaceutical industry for maintaining stable microclimate conditions within cleanroom environments, ensuring product quality, and complying with Good Manufacturing Practices (GMP or CPOB in Indonesia). This system functions to regulate temperature, relative humidity, airflow, and air quality to prevent contamination and ensure thermal comfort. This study aims to design an air handling system for a cleanroom at a pharmaceutical facility (PT X) located in Semarang, with a specific focus on mitigating the risk of uncontrolled condensation within the air supply duct. Cooling load calculations were performed using the Cooling Load Temperature Difference (CLTD) method as a manual approach and then validated using Hourly Analysis Program (HAP) software to enhance design accuracy and efficiency. Psychrometric analysis was also conducted to better understand the air properties and determine the optimal supply air temperature. The outcome of this research is expected to deliver an air handling system design that not only complies with CPOB standards but is also energy-efficient and capable of effectively controlling temperature and humidity to prevent condensation. Keywords: Air handling system, cleanroom, condensation control, CLTD , CPOB Sistem tata udara merupakan komponen sangat penting dalam industri farmasi untuk menjaga kestabilan kondisi mikroklimat ruangan, untuk memastikan kualitas produk, serta memenuhi persyaratan Cara Pembuatan Obat yang Baik (CPOB). Sistem tata udara berfungsi untuk mengendalikan suhu, kelembaban relatif, aliran udara serta kualitas udara guna mencegah kontaminasi dan menjaga kenyamanan termal. Penelitian ini bertujuan untuk merancang sistem tata udara pada salah satu ruang bersih di industri farmasi PT X di kota Semarang, dengan fokus penelitian pada pengendalian risiko kondensasi yang tidak terkendali pada saluran udara. Perhitungan beban pendinginan dilakukan menggunakan metode Cooling Load Temperature Difference (CLTD) sebagai metode manual, yang kemudian divalidasi menggunakan perangkat lunak Hourly Analysis Program (HAP) guna meningkatkan akurasi dan efisiensi perancangan. Analisis psikometrik turut dilakukan untuk memahami karakteristik udara serta menentukan suhu suplai udara yang optimal. Hasil dari penelitian ini diharapkan dapat menghasilkan desain sistem tata udara yang tidak hanya sesuai standar CPOB, namun efisien dalam penggunaan energi serta mampu mengendalikan suhu dan kelembaban secara efektif guna mencegah terjadinya kondensasi. Kata kunci : Sistem tata udara, Ruang bersih, Kondensasi, CLTD, CPOB
| Item Type: | Thesis (S1) |
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| Call Number CD: | FT/MSN. 25 114 |
| NIM/NIDN Creators: | 41323110061 |
| Uncontrolled Keywords: | Sistem tata udara, Ruang bersih, Kondensasi, CLTD, CPOB |
| Subjects: | 500 Natural Science and Mathematics/Ilmu-ilmu Alam dan Matematika > 530 Physics/Fisika > 536 Heat/Panas > 536.5 Temperature/Temperatur, Suhu 600 Technology/Teknologi > 610 Medical, Medicine, and Health Sciences/Ilmu Kedokteran, Ilmu Pengobatan dan Ilmu Kesehatan > 615 Pharmacology and Therapeutics/Farmakologi dan Terapi Farmakologi 600 Technology/Teknologi > 690 Buildings/Teknik Bangunan > 697 Heating, ventilating, air-conditioning engineering/Teknik Pemanasan Rumah, Teknik Pemanas Ruangan, Teknik Ventilasi dan Pendingin Ruangan AC |
| Divisions: | Fakultas Teknik > Teknik Mesin |
| Depositing User: | khalimah |
| Date Deposited: | 03 Oct 2025 08:10 |
| Last Modified: | 03 Oct 2025 08:10 |
| URI: | http://repository.mercubuana.ac.id/id/eprint/98742 |
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